Two cycloartanes-type triterpenoid from Homonoia riparia Lour
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چکیده
منابع مشابه
A new cycloartane-type triterpenoid saponin xanthine oxidase inhibitor from Homonoia riparia Lour.
A new cycloartane-type triterpenoid saponin named riparsaponin (1) was isolated from the stem of Homonoia riparia Lour together with six known compounds. The structure of riparsaponin was determined by using NMR and mass spectroscopy and X-ray crystallography techniques. Additionally, riparsaponin has a significant inhibitory effect on xanthine oxidase in vitro, and the IC50 was 11.16 nmol/mL.
متن کاملDammarane-type triterpenoids as 11β-HSD1 inhibitors from Homonoia riparia.
An exploration for 11β-HSD1 inhibitors from Homonoia riparia returned eight new dammarane-type triterpenoids, horipenoids A–H (1–8), and a known oleanane-type triterpenoid (9). Their structures were elucidated on the basis of comprehensive analysis of spectroscopic data, and the absolute configuration of horipenoid E (5) was established by single crystal X-ray crystallography. Compounds 1–4 rep...
متن کاملAntioxidant and Nephroprotective Activities of the Extract and Fractions of Homonoia riparia Lour
BACKGROUND Homonoia riparia is a plant, which is widely used in the indigenous system of medicine for the treatment of urolithiasis, renal disorders and inflammatory conditions. This is the first report on the antioxidant and nephroprotective activities of whole plant of H. riparia. OBJECTIVE The present study aims at investigating the in vitro antioxidant and nephroprotective activity of the...
متن کاملHomonoia riparia and its major component, myricitrin, inhibit high glucose-induced apoptosis of human retinal pericytes
BACKGROUND The loss of retinal pericytes is one of the earliest changes associated with diabetic retinopathy (DR). Chronic hyperglycemia induces apoptosis of these cells, leading to the onset and progression of DR. In this study, we investigated the effects of Homonoia riparia (H. riparia) and its major component, myricitrin, on high glucose (HG)-induced apoptosis of primary human retinal peric...
متن کاملEvaluation of Antioxidant Activity of Homonoia Riparia Lour., Kirganelia Reticulata (poir) Baill., Phyllanthus Fraternus Webster and Pedilanthus Tithymaloides (linn.) Poit. and Its Correlation with the Total Phenolic and Flavonoid Contents
Plants of Euphorbiaceae are used to cure various diseases in traditional systems of medicine. For present study, Homonoia riparia, Kirganelia reticulata, Phyllanthus fraternus and Pedilanthus tithymaloides were selected on the basis of their availability and antimicrobial activity. Plant phenolics and flavonoids are known to possess antioxidant activity. Hence, it was decided to evaluate the an...
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ژورنال
عنوان ژورنال: Vietnam Journal of Chemistry
سال: 2017
ISSN: 0866-7144,0866-7144
DOI: 10.15625/2525-2321.2017-00497